MCC have finalised their squad – including Worcestershire paceman Charlie Morris – and itinerary for the two week tour of South Africa.
Eight county players are named in a party which will be skippered by Derbyshire's Wes Durston.
Nick Compton had originally been earmarked to lead the side before his call-up into the England squad to face the Proteas this winter.
Middlesex's managing director and former England paceman Angus Fraser will be the tour manager with the squad flying out on December 27 and returning on January 10.
MCC will play six games on the tour against a variety of opposition including KwaZulu Natal, Crusaders and a Western Province Cricket Association XI.
They will also give a coaching session to local children from the Khayelitsha township in Cape Town.
John Stephenson, MCC Head of Cricket, said: “This is the Club’s final tour of the year and it promises to be a fantastic one.
"We have picked a very talented squad with plenty of current and former professionals involved, as we are expecting a very high standard of cricket.
"We will be playing two matches on sixth day Test match pitches at Kingsmead and Newlands, which I’m sure will be an enjoyable experience for all the players.
"Most importantly, they will be ambassadors for MCC and its work in a major Test playing nation, and I’m sure they will be a credit to the Club.”
Angus Fraser (Manager) Middlesex CCC
Wes Durston (Captain) Derbyshire CCC
Neil Dexter Leicestershire CCC
Ned Eckersley Leicestershire CCC
Chris Wright Warwickshire CCC
Owais Shah Hampshire CCC
John Simpson Middlesex CCC
CHARLIE MORRIS WORCESTERSHIRE CCC
Matthew Hunn Kent CCC
Chris Peploe Ealing CC
Tom Rash Suffolk CCC
George Thurstance Bedfordshire CCC
Graham Grace Eastern Province CC
Jonathan Marsden Derbyshire Academy, Oxford MCCU
Andre Geldenhuys Stellenbosch CC
Jeff Evans (Umpire)
Pete Waxman (Physio)
30 December MCC v Crusaders (50 overs) Crusaders Club
31 December MCC v KwaZulu-Natal XI (50 overs) Kingsmead
3-4 January MCC v Western Province Cricket Association XI (two days) Vineyard Oval
6 January MCC v St Augustine’s CC (40 overs) Basil D’Oliveira Sports Complex
7 January MCC v Western Province Academy (50 overs) Newlands
8 January MCC v Western Province XI (50 overs) Boland Park